Vital Signs – Titrations
Antacids are often used to treat heartburn. When acidic stomach content comes back up the esophagus heartburn patients experience a burning sensation behind the breastbone. Our biochemist campers used titrations to find the appropriate amount of base to neutralize the acid. Their job was to change the pH from 1 to 7 (neutral), by adding the base. At the end of the activity, campers took the calculated amount of base (antacid), put it into a capsule that allows for diffusion, and set it into the acid (represents heartburn). On Friday they will check the results to see if the acid was neutralized!
Ask your camper: If we start with 10mL of the acid, hydrochloric acid, how many mL of the base, sodium hydroxide, so we need to add to reach a pH of 7? The same amount – 10mL! The acid and base are the same concentration, and at opposite ends of the pH scale.